What is it for?

Product Features

Polynucleotides (1% High Purity) are purified biomolecules recognized as master biostimulators in aesthetic medicine. These advanced compounds work at the cellular level to enhance your skin's natural regenerative capacity, promoting DNA repair and cellular renewal. By stimulating fibroblast proliferation and collagen synthesis, polynucleotides strengthen the skin barrier, improve extracellular matrix production, and boost elastin formation. This intensive 1% concentration delivers powerful anti-aging effects, promoting angiogenesis for better microcirculation while reducing inflammation and oxidative stress in the delicate under-eye area for visibly brighter, firmer, and more resilient skin.

Benefits and Effects

  • Brightens Dark Circles & Skin Tone
  • Reduces Fine Lines & Wrinkles
  • Firms and Tightens Skin
  • Minimizes Pores & Supports Scar Recovery

Key Ingredients

  • Polynucleotides (PN) 1% (20mg/2ml)

Product details

Skin Problems to Address
  • Dark circles and under-eye hyperpigmentation – Brightens the periorbital area by improving microcirculation and reducing vascular discoloration
  • Fine lines and wrinkles around the eyes – Stimulates collagen and elastin production to smooth crow's feet and periorbital lines
  • Under-eye puffiness and bags – Enhances lymphatic drainage and reduces fluid retention for a refreshed appearance
  • Skin laxity and loss of firmness – Strengthens dermal structure through enhanced fibroblast activity and ECM restoration
  • Enlarged pores – Refines skin texture and minimizes pore appearance through improved skin density
  • Post-inflammatory scarring – Supports tissue repair and accelerates healing processes
Ingrediens and Storage

Active Ingredient

Polynucleotides 20mg/2ml (1% High Purity)

Storage

Store in a cool, dry place at a temperature of 1 to 30 ℃. Keep away from direct sunlight.

Capacity

2ml x 1pcs/ Box

Expiration

36 months from the production date (indicated on the box)

Country of origin

South Korea

How to use

What is Microneedling?

Microneedling is a minimally invasive skin care treatment that uses tiny needles to cause micro-injuries in the skin, activating your body's natural healing process. This increases collagen and elastin synthesis, which helps to revitalize your skin from the inside out. 

The active ingredients of the ampoule penetrate deep into the skin through the fine pores on the skin's surface, increasing absorption efficiency.

How to use

  1. Prepare your skin for microneedling procedure.
  2. Begin the microneedling treatment in 2-3 minutes after applying the booster ampoule. The booster ampoule comes in various types to meet your skin's needs: Acne, Salmon, Peptide Gold, Whitening, Aqua, Citron & Calendula, Hyaluronic Acid, Microbiome, Idebenone, and Collagen.
  3. Apply aftercare cream: Peelieve Cica Cream or Repair Cream (Eve Vegan)
Precautions
  • This product should only be used by trained professionals or doctors.
  • This product is a medical device.
  • Discontinue use and consult a dermatologist immediately if adverse reactions such as redness, swelling, or itching occur during use, or if such symptoms develop upon sun exposure after application.
  • Do not apply to damaged, wounded, or irritated skin areas.
How long does shipping take?
  • How long does shipping take?
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Complete your setup

Cartridges sold separately? Not here — a free 10-pack of 14-pin cartridges comes with every A20 ($79 value).

Dr. Pen A20 14-pin replacement cartridges

Replacement cartridges

14-pin Cartridges · 10-pack

A fresh cartridge for each session. Your first 10-pack is included with every A20.

$79

Stayve microneedling ampoules

Serum selection

Serum for your concern

Acne scars / marks Dark spots / tone Lines / firmness Hydration / prep

Salmon DNA Gold · Acne Stem Cell · Whitening Stem Cell · Medisco HA · Collagen · Peptide Gold

Zensa topical anesthetic cream

Prep option

Zensa Numbing Cream

A separate prep option for customers who choose to use a numbing cream as part of their routine.

$39

Serums and topical products are sold separately. Review each product’s directions and suitability before use.

FDA 510(k) cleared

Free 2–5 Day UPS

60-Day Returns

3-Year Warranty